LILRB Ligand
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ORS-14
0 ImagesArt. -Nr.: HY-184689CAS. Nr.: 1311892-52-0ORS-14 is a LILRB4/ILT3 ligand with a Kd of 85.2 nM for human receptors. ORS-14 blocks SCG2-mediated LILRB4 signaling pathway, reverses SCG2-mediated immunosuppression, restores cytokine production, reduces tumor cell viability, recovers cytotoxic T cell function, and increases the frequency of granzyme B+ CD8+ T cells. ORS-14 can be used in research related to colorectal cancer and acute myeloid leukemia.
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ORS-22
0 ImagesArt. -Nr.: HY-184688CAS. Nr.: 1311612-43-7ORS-22 is an immunomodulator with a Kd value of 9.2 nM for human LILRB4. ORS-22 binds directly to the extracellular domain of LILRB4, reverses immunosuppression, restores cytotoxic T cell function, recovers cytokine production, and reduces tumor cell viability. ORS-22 can be used in research related to colorectal cancer and acute myeloid leukemia.
