Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1267)
Related Products (1267)
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DSPE-PEG2000-CH2COOH
0 ImagesCat. No.: HY-140737DSPE-PEG2000-CH2COOH is a functionalized PEG derivative widely used in drug delivery and chemical synthesis.
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18:1 Dodecanyl PE
0 ImagesCat. No.: HY-W800795CAS No.: 474923-47-2Synonyms: DOPE-NG; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanoyl)18:1 Dodecanyl PE is a carboxylic acid-functionalized lipid with a ten carbon linker to a phosphoethanolamine bound to two oleic acid tails.
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DSPE-PEG5000-VHPKQHRGGSKGC
0 ImagesCat. No.: HY-182101CDSPE-PEG5000-VHPKQHRGGSKGC is a targeted modified phospholipid-polyethylene glycol conjugate covalently coupled to DSPE, PEG, and the vascular-targeting peptide VHPKQHRGGSKGC. DSPE-PEG5000-VHPKQHRGGSKGC can be used in research on tumor vascular imaging and vascular-targeted drug delivery.
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DMG-PEG1000-Glucose
0 ImagesCat. No.: HY-183156DMG-PEG1000-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG1000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG3400-RVG29
0 ImagesCat. No.: HY-172705ADSPE-PEG3400-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG3400-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG3400-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions
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DSPE-PEG2000-Asp6
0 ImagesCat. No.: HY-182092BDSPE-PEG2000-Asp6 is a PEG compound which composed of DSPE and a Asp6 peptide. DSPE-PEG2000-Asp6 achieves bone-targeted delivery of drugs or imaging agents by binding to bone tissue with the Asp6 peptide through high affinity.
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18:1 MPB PE
0 ImagesCat. No.: HY-W800788CAS No.: 384835-49-818:1 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a phenyl maleimide group.
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mono-Pal-MTO
0 ImagesCat. No.: HY-148701CAS No.: 1349197-89-2mono-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity.
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Phospholipid-PEG20000-Biotin
0 ImagesCat. No.: HY-147207EPhospholipid-PEG20000-Biotin is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG20000-Biotin can interact with avidinylated antibodies. Phospholipid-PEG20000-Biotin can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation.
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DMG-PEG5000-Glucose
0 ImagesCat. No.: HY-183156CDMG-PEG5000-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG5000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG12 carboxy sodium
0 ImagesCat. No.: HY-N16299CAS No.: 3091879-93-2DSPE-PEG12 carboxy sodium is a lipid that consists of a DSPE-PEG12 unit conjugated to a carboxy group. DSPE-PEG12 carboxy sodium can be used to prepare lipid nanoparticles for drug delivery.
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4A3-SC10
0 ImagesCat. No.: HY-W1130429CAS No.: 1857340-80-74A3-SC10 is an ionizable cationic lipid (pKa = 6.57) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. 4A3-SC10 can be used for drug delivery in cancer.
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DSPE-PEG3400-pPB
0 ImagesCat. No.: HY-172275CDSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery.
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Dios-Arg diTFA
0 ImagesCat. No.: HY-129990CAS No.: 1807353-31-6Dios-Arg diTFA, a cationic lipid with an arginine-bearing headgroup, shows obvious double bond proton signals at around 5.2-5.3 ppm. Dios-Arg diTFA is used, coupled to DOPE, to bind siRNA and plasmid to for cationic LNPs for intracellular transport.
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DSPE-PEG2000-TH
0 ImagesCat. No.: HY-172693DSPE-PEG2000-TH is a PEG compound which composed of DSPE and a pH-responsive cell penetrating peptide (TH). TH is activated in an acidic environment (such as the tumor microenvironment) and can selectively carry small molecules, oligonucleotides, proteins, etc. into tumor cells.
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DSPE-PEG1000-PP1
0 ImagesCat. No.: HY-172707DSPE-PEG1000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG1000-PP1 can be used for drug delivery.
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DSPE-PEG3400-SP94
0 ImagesCat. No.: HY-172500ADSPE-PEG3400-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG3400-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.
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DMG-PEG5000-COOH
0 ImagesCat. No.: HY-200288CDMG-PEG5000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
