2. Signaling Pathways
  3. Stem Cell/Wnt
  4. sFRP-1
  5. sFRP-1 Inhibitor

sFRP-1 Inhibitor

sFRP-1 Inhibitors (6):

Cat. No. Product Name Effect Purity
  • HY-10858
    WAY 316606
    		Inhibitor 99.24%
    WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC50 of 0.5 μM.
  • HY-117738
    Benarthin
    		Inhibitor
    Benarthin is a catechol-type siderophore isolated from the marine actinomycete Streptomyces YM5-799 that exhibits iron-chelating properties.
  • HY-10860
    WAY-362692
    		Inhibitor 99.91%
    WAY-362692 is a secreted frizzled-related protein (sFRP-1) inhibitor (IC50 of 0.02 μM), targeting the netrin domain of sFRP-1. WAY-362692 can competitively inhibit the interaction between sFRP-1 and Wnt proteins, and activate the Wnt/β-catenin signaling pathway (EC50 = 0.03 μM). WAY-362692 can activate osteoblasts and promote bone remodeling. WAY-362692 can be used for the research of metabolic disease, such as osteoporosis.
  • HY-10858A
    WAY 316606 hydrochloride
    		Inhibitor 98.04%
    WAY 316606 hydrochloride is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC50 of 0.5 μM.
  • HY-202887
    BCN512
    		Inhibitor 99.77%
    BCN512 is an inhibitor of SFRP1 that can inhibit tissue fibrosis. BCN512 can be used in the research about inflammatory diseases.
  • HY-10858R
    WAY 316606 (Standard)
    		Inhibitor
    WAY 316606 (Standard) is the analytical standard of WAY 316606 (HY-10858). This product is intended for research and analytical applications. WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC50 of 0.5 μM.