2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Serpin
  5. Serpin Inhibitor

Serpin Inhibitor

Serpin Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-134858
    GSK716
    		Inhibitor 99.77%
    GSK716 (A1AT modulator 1) is an orally active Z α1-antitrypsin (Z-A1AT) inhibitor with a pIC50 of 8.3. GSK716 binds a cryptic Z α1-antitrypsin pocket, stabilizes monomeric folding intermediates, blocks polymerization, and increases monomer secretion. GSK716 acts on select sensitive α1-antitrypsin variants but fails to affect resistant variants. GSK716 can be used for the research of α1-antitrypsin deficiency and α1-antitrypsin deficiency-associated liver disease.
  • HY-177619A
    Belcesiran sodium
    		Inhibitor
    Belcesiran is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.
  • HY-177619
    Belcesiran
    		Inhibitor
    Belcesiran, a siRNA, is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.
  • HY-177619B
    Belcesiran sodium scrambled negative control
    		Inhibitor
    Belcesiran sodium scrambled negative control is the sequence scrambled negative control of Belcesiran sodium.
  • HY-177075
    Crovozalpon
    		Inhibitor
    Crovozalpon (Compound 4) is an inhibitor of alplha-1-antitrypsin. Crovozalpon can be used as a prodrug. Crovozalpon can be studied in research for diseases associated with alplha-1-antitrypsin