AB-343
AB-343 is a selective covalent inhibitor of SARS-CoV-2 Mpro, with an IC50 of 8 nM and a Ki of 2.8 nM. AB-343 can effectively inhibit the main proteases of SARS-CoV-2 and many other coronaviruses, and is also active against some resistant variants. AB-343 can be used in the research of treating coronavirus infection-related diseases.
For research use only. We do not sell to patients.
- CAS No.: 3077209-48-1
- Formula: C26H34F5N5O4
- Molecular Weight:575.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 3077209-48-1
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Molecular Weight 575.57
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Formula C26H34F5N5O4
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SMILES
O=C([C@H](NC(C(F)(F)F)=O)CC1CCC1)N2[C@H]3CC[C@@H]([C@H]2C(N[C@H](C#N)C[C@H]4CC(C)(NC4=O)C)=O)C(F)(F)C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)