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Cat. No.: HY-N10973

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Abiesadine F

Abiesadine F is a diterpenoid isolated from Abies georgei Orr.

For research use only. We do not sell to patients.

CAS No.: 1210347-46-8
Formula: C₂₄H₃₄O₅
Molecular Weight:402.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Abiesadine F Chemical Structure

CAS No.: 1210347-46-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Abiesadine F is a diterpenoid isolated from Abies georgei Orr^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>10 μM Compound: 28	Cytotoxicity in human A549 cells by SRB assay Cytotoxicity in human A549 cells by SRB assay	[PMID: 26812172]
HCT-116	IC₅₀	>10 μM Compound: 28	Cytotoxicity in human HCT116 cells by SRB assay Cytotoxicity in human HCT116 cells by SRB assay	[PMID: 26812172]
HEK293	IC₅₀	>100 μg/mL Compound: 6, Abiesadine F	Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells	[PMID: 20022253]
LoVo	IC₅₀	>25 μg/mL Compound: 6, Abiesadine F	Antiproliferative activity against human LoVo cells Antiproliferative activity against human LoVo cells	[PMID: 20022253]
QGY-7703	IC₅₀	>25 μg/mL Compound: 6, Abiesadine F	Antiproliferative activity against human QGY7703 cells Antiproliferative activity against human QGY7703 cells	[PMID: 20022253]
RAW264.7	IC₅₀	>100 μg/mL Compound: 6, Abiesadine F	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release	[PMID: 20022253]
SK-MEL-2	IC₅₀	>10 μM Compound: 28	Cytotoxicity in human SK-MEL-2 cells by SRB assay Cytotoxicity in human SK-MEL-2 cells by SRB assay	[PMID: 26812172]
SK-OV-3	IC₅₀	>10 μM Compound: 28	Cytotoxicity in human SKOV3 cells by SRB assay Cytotoxicity in human SKOV3 cells by SRB assay	[PMID: 26812172]

Chemical Information

CAS No. 1210347-46-8
Molecular Weight 402.52
Formula C₂₄H₃₄O₅
SMILES

C[C@@]12[C@](C[C@H](C3=CC(C(C)C)=CC=C32)O)([H])[C@@](C)(CCC1)COC(CCC(O)=O)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Pinaceae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xian-Wen Yang, et al. Isolation, structure, and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. Bioorg Med Chem. 2010 Jan 15;18(2):744-54. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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