2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. LXR
  4. Acetyl podocarpic acid anhydride

Acetyl podocarpic acid anhydride  (Synonyms: Acetylpodocarpic dimer; APD)

Cat. No.: HY-125772 Purity: ≥99.0%
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Acetyl podocarpic acid anhydride is a potent, semisynthetic liver X receptor(LXR) agonist derived from extracts of the mayapple. Acetyl podocarpic acid anhydride has the potential to be useful for the prevention and research of atherosclerosis, especially in the context of low HDL levels.

For research use only. We do not sell to patients.

Acetyl podocarpic acid anhydride Chemical Structure

Acetyl podocarpic acid anhydride Chemical Structure

CAS No. : 344327-48-6

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5 mg USD 330 In-stock
10 mg USD 530 In-stock
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Based on 1 publication(s) in Google Scholar

Acetyl podocarpic acid anhydride Related Antibodies

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Description

Acetyl podocarpic acid anhydride is a potent, semisynthetic liver X receptor(LXR) agonist derived from extracts of the mayapple. Acetyl podocarpic acid anhydride has the potential to be useful for the prevention and research of atherosclerosis, especially in the context of low HDL levels[1].

Clinical Trial
Molecular Weight

614.77

Formula

C38H46O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OC([C@@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=CC(OC(C)=O)=C3)=O)[C@@]4(C)CCC[C@]5(C)C6=C(CC[C@@]45[H])C=CC(OC(C)=O)=C6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : 1 mg/mL (1.63 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6266 mL 8.1331 mL 16.2662 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (245 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF 1 mM 1.6266 mL 8.1331 mL 16.2662 mL 40.6656 mL
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Acetyl podocarpic acid anhydride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acetyl podocarpic acid anhydride344327-48-6Acetylpodocarpic dimer APDLXRLiver X receptorInhibitorinhibitorinhibit

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