AChE/BChE/MAO-A-IN-1
AChE/BChE/MAO-A-IN-1 (Compound 5c) is a multi-target inhibitor with IC₅₀ values for AChE, BChE, and MAO-A of 78.7, 22.63, and 0.84 μM respectively. AChE/BChE/MAO-A-IN-1 can be used for the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C23H17FN4O3S2
- Molecular Weight:480.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
BChE 22.63 μM (IC50) |
AChE 78.7 μM (IC50) |
MAO-A 0.84 μM (IC50) |
Chemical Information
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Molecular Weight 480.53
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Formula C23H17FN4O3S2
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SMILES
O=S(C1=C2N=CC=CC2=CC=C1)(OC3=CC=C(/C=N/NC(NC4=CC=CC=C4F)=S)C=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)