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Cat. No.: HY-187051

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AdemG Phosphoramidite

AdemG Phosphoramidite is a ligand-conjugated phosphoramidite synthon. AdemG Phosphoramidite can be used for the synthesis of GalNAc-conjugated siRNA and DsiRNA for liver-targeted gene silencing.

For research use only. We do not sell to patients.

CAS No.: 1953147-04-0
Formula: C₆₈H₉₂N₉O₂₁P
Molecular Weight:1402.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AdemG Phosphoramidite Chemical Structure

CAS No.: 1953147-04-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

AdemG Phosphoramidite is a ligand-conjugated phosphoramidite synthon. AdemG Phosphoramidite can be used for the synthesis of GalNAc-conjugated siRNA and DsiRNA for liver-targeted gene silencing^[1].

Chemical Information

CAS No. 1953147-04-0
Molecular Weight 1402.50
Formula C₆₈H₉₂N₉O₂₁P
SMILES

C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCOCCOCCNC(CCCCO[C@H]2[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O2)=O)[C@@H](O1)N3C4=C(N=C3)C(=O)N=C(NC(C(C)C)=O)N4)(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. BROWN B D, et al. LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS. WO2016100401A1. 23.06.2016

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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