Alytesin
Alytesin, a bombesin-like peptide, is found in extracts of the skin of Alytes obstetricans. Alytesin reduces gastric acid secretion and induces hypertension. Alytesin also induces short-term anorexigenic effects in neonatal chicks
For research use only. We do not sell to patients.
- CAS No.: 31078-12-3
- Formula: C68H106N22O17S
- Molecular Weight:1535.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-103286
PD176252BB1/BB2 Antagonist -
HY-103281
LitorinBombesin Receptor Agonist -
HY-P0195
BombesinBombesin Receptor Modulator -
HY-103286R
PD176252 (Standard)Reference Standard -
![[D-Phe12,Leu14]-Bombesin](https://file.medchemexpress.com/product_pic/hy-103287.gif)
HY-103287
[D-Phe12,Leu14]-BombesinBombesin Receptor Antagonist -
![[D-Phe12]-Bombesin](https://file.medchemexpress.com/product_pic/hy-103282.gif)
HY-103282
[D-Phe12]-BombesinBombesin Receptor Antagonist -
HY-103279
BIM187Bombesin Receptor Agonist -
HY-P0238
Gastrin-Releasing Peptide, humanGastrin Releasing Peptide -
HY-P0241
Neuromedin BEndogenous Metabolite -
HY-14342
MK-5046BRS-3 Agonist -
HY-103285
GRP (porcine)Gastrin Release Stimulator -
HY-103277
BIM 23042NMB-R Antagonist
All Endogenous Metabolite Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 31078-12-3
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Molecular Weight 1535.77
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Formula C68H106N22O17S
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Sequence
{Glp}-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
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Sequence Shortening
{Glp}-GRLGTQWAVGHLM-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Cardiovascular Diseases
Cardiovascular disease can be modeled as maladaptive cardiac remodeling, where ischemic injury or pressure overload activates inflammatory signaling, fibroblast activation, extracellular-matrix deposition, cardiomyocyte hypertrophy, vascular remodeling, and progressive ventricular dysfunction. The TGF-β/SMAD axis is a central profibrotic pathway after myocardial injury and pressure overload, while innate immune and cytokine pathways regulate leukocyte recruitment, scar formation, and adverse remodeling. Key unresolved questions include which inflammatory signals are reparative versus harmful, when fibrosis is protective versus maladaptive, and whether pathway inhibition improves function without weakening necessary infarct healing or compensatory remodeling.
Purity & Documentation
References
[1]. Guglietta A, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. [Content Brief]
[2]. Erspamer V, et al. Some pharmacological actions of alytesin and bombesin. J Pharm Pharmacol. 1970 Nov;22(11):875-6. [Content Brief]
[3]. Cline MA, et al. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Alytesin Related Classifications
HY-103276 Related Classifications
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