Ammonium trifluoroacetate
Based on 1 Customer Validation
Ammonium trifluoroacetate (Trifluoroacetic acid amine) is a metal-free, biodegradable quaternary ammonium salt catalyst with weakly acidic characteristics.
For research use only. We do not sell to patients.
- Purity: 99.29%
- CAS No.: 3336-58-1
- Formula: CF3CO2NH4
- Molecular Weight:131.05
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Ammonium trifluoroacetate promotes the microwave-accelerated conjugate addition reaction between 2-arylindoles and β-nitrostyrenes[1].
Ammonium trifluoroacetate acts as a solid support for the synthesis of 3,4-dihydropyrimidin-2 (1H)-one[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3336-58-1
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Appearance Solid
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Molecular Weight 131.05
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Formula CF3CO2NH4
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Color White to off-white
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SMILES
O=C(C(F)(F)F)O.N
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Synonyms
Trifluoroacetic acid amine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (763.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 100 mg/mL (763.07 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Kulkarni PM, et al. Microwave-accelerated conjugate addition of 2-arylindoles to substituted β-nitrostyrenes in the presence of ammonium trifluoroacetate: an efficient approach for the synthesis of a novel class of CB1 cannabinoid receptor allosteric modulators. Journal of heterocyclic chemistry. 2017 May;54(3):2079-2084. [Content Brief]
[2].
Raju C, et al. Ammonium Trifluoroacetate-Mediated Synthesis of 3,4-dihydropyrimidin-2(1H)-ones. ISRN Org Chem. 2011 Nov 13;2011:273136.
[Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 7.6307 mL | 38.1534 mL | 76.3068 mL | 190.7669 mL |
| 5 mM | 1.5261 mL | 7.6307 mL | 15.2614 mL | 38.1534 mL | |
| 10 mM | 0.7631 mL | 3.8153 mL | 7.6307 mL | 19.0767 mL | |
| 15 mM | 0.5087 mL | 2.5436 mL | 5.0871 mL | 12.7178 mL | |
| 20 mM | 0.3815 mL | 1.9077 mL | 3.8153 mL | 9.5383 mL | |
| 25 mM | 0.3052 mL | 1.5261 mL | 3.0523 mL | 7.6307 mL | |
| 30 mM | 0.2544 mL | 1.2718 mL | 2.5436 mL | 6.3589 mL | |
| 40 mM | 0.1908 mL | 0.9538 mL | 1.9077 mL | 4.7692 mL | |
| 50 mM | 0.1526 mL | 0.7631 mL | 1.5261 mL | 3.8153 mL | |
| 60 mM | 0.1272 mL | 0.6359 mL | 1.2718 mL | 3.1794 mL | |
| 80 mM | 0.0954 mL | 0.4769 mL | 0.9538 mL | 2.3846 mL | |
| 100 mM | 0.0763 mL | 0.3815 mL | 0.7631 mL | 1.9077 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Ammonium trifluoroacetate Related Classifications
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