Anti-Mouse CD90.2 Antibody (30H12)
Based on 1 Customer Validation
Anti-Mouse CD90.2 Antibody (30H12) is an anti-mouse CD90.2 IgG2b antibody inhibitor derived from host Rat. Anti-Mouse CD90.2 Antibody (30H12) can deplete innate lymphoid cells (ILC) and T cells. Anti-Mouse CD90.2 Antibody (30H12) can be used for the researches of infection, inflammation and immunology, such as Yersinia enterocolitica infection and airway inflammation.
For research use only. We do not sell to patients.
- Purity: 95.00%
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Rat IgG2b kappa
Human/Mouse
Anti-Mouse CD90.2 Antibody (30H12) (500 μg/mouse, i.p., every other day for 4 times) depletes innate lymphoid 2 cells (ILC2) and reduces airway inflammation and hyperresponsiveness in ozone-induced mice[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rag1−/− mice with Yersinia enterocolitica infection[1]
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Dosage:500 μg/mouse
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Administration:Intraperitoneally injection, at days -4, -1, 2, 5
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Result:Depleted ILC and most NK cells in the small intestinal lamina propria.
Had a decreased survival rate and rapid weight loss.
Increased bacterial burden in the ileum, spleen and liver.
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Animal Model:Ozone-induced mice[2]
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Dosage:100 μg/mouse
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Administration:Intraperitoneally injection, every other day for 4 times
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Result:Depleted ILC2 and T cells.
Reduced total cell count and neutrophil and abolished eosinophils in the BAL fluid.
Abolished IL-5 release in the BAL.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
in vivo ILC depletion; in vivo T cell depletion; Western blot
Chemical Information
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Appearance Liquid
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Molecular Weight 150 kDa
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Color Colorless to light yellow
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SMILES
[Anti-Mouse CD90.2 Antibody (30H12)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (260 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Seo GY, et al. LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection. Cell Host Microbe. 2018 Aug 8;24(2):249-260.e4. [Content Brief]
[2]. Yang Q, et al. Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice. J Allergy Clin Immunol. 2016 Feb;137(2):571-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-Mouse CD90.2 Antibody (30H12) Related Classifications
HY-P99131 Related Classifications
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