Anti-MRSA agent 4
Anti-MRSA agent 4 (compound 7a) is a potent and selective growth inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA), with MIC ≤ 0.26 µM. Anti-MRSA agent 4 exhibits no cytotoxic and no hemolytic activity in HEK293 cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C48H68F6N4O8
- 分子量:943.07
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
MIC: ≤ 0.26 µM (MRSA)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>33.9 μM
Compound: 7a
|
Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 20 hrs by resazurin dye based assay
Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 20 hrs by resazurin dye based assay
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[PMID: 35477062] |
化学情報
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分子量 943.07
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分子式 C48H68F6N4O8
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SMILES
[H][C@@]12CCC3=C([C@]1(CCC[C@@]2(C(NCCCNCCCCNCCCNC([C@]4(CCC[C@@]5(C6=C(CC[C@@]45[H])C=CC(O)=C6)C)C)=O)=O)C)C)C=C(C=C3)O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)