Anti-West Nile/dengue virus E protein Antibody (E60)
Anti-West Nile/dengue virus E protein Antibody (E60) is mouse-derived IgG2a κ type antibody inhibitor, targeting to West Nile/dengue virus E protein. Anti-West Nile/dengue virus E protein Antibody (E60) can cross-neutralize West Nile virus (WNV) and dengue virus (DENV) envelope (E) protein. Anti-West Nile/dengue virus E protein Antibody (E60) can be used for the researches of WNV and DENV infection.
For research use only. We do not sell to patients.
- Molecular Weight:150 kDa
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Isotype
Mouse IgG2a kappa
Recommend Isotype Controls
Species Reactivity
Virus
IC50 & Target
West Nile/dengue virus E protein
In Vitro
Anti-West Nile/dengue virus E protein Antibody (E60) (1 h) increases neutralization with dengue virus (DENV) than West Nile virus (WNV)[1].
Anti-West Nile/dengue virus E protein Antibody (E60) (10 μg/mL, 16 h) displays limited neutralization of WT Zika virus (ZIKV) reporter virus particles (RVPs)[2].
Anti-West Nile/dengue virus E protein Antibody (E60) completely neutralizes mature RVP preparations of ZIKV containing either the DENV1 or DENV2 loop, with EC50 of 64.4 and 176.6 ng/mL, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
-
Product Image
Application
Neutralization of WNV; Neutralization of DENV1,2,3,4
Chemical Information
-
Molecular Weight 150 kDa
-
SMILES
[Anti-West Nile/dengue virus E protein Antibody (E60)]
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Dowd KA, et al. A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus. PLoS Pathog. 2011 Jun;7(6):e1002111. [Content Brief]
[2]. Goo L, et al. The Zika virus envelope protein glycan loop regulates virion antigenicity. Virology. 2018 Feb;515:191-202. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-West Nile/dengue virus E protein Antibody (E60) Related Classifications
HY-P990817 Related Classifications
Powered by Bioz