ARL13B Antibody (YA6956)

Cat. No.: HY-P87273: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

ARL13B Antibody (YA6956) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ARL13B.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
Documentation

Description

ARL13B Antibody (YA6956) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ARL13B.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 49 kDa;

Observed band size: 49 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q3SXY8

Immunogen

Synthetic peptide within human ARL13B aa 370-428.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000

Sensitivity	Endogenous	Purity	Protein G affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from HEK293 (lane 1(20μg)) 、HL-60 (lane 2(20μg)) 、HepG2 (lane 3(20μg)) and K562 (lane 4(20μg)) using ARL13B Antibody (HY-P87273) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/5000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

Background

Function：Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze fit; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. Plays a role in ciliar trafficking of phosphatidylinositol phosphatase INPP5E in ciliogenesis (PubMed:38219074). May regulate ARF6- and RAB22A-dependent endocytic recycling traffic (PubMed:23223633)

Subcellular Localization：Cell projection, cilium membrane,Cell projection, cilium,Cell membrane,Cytoplasm, cytoskeleton

Expression：
Tissue_Specificity: Expressed in the developing brain

Isoforms & Post-Translational Modification：Q3SXY8 has three isomers: Q3SXY8-1: 48643 Da (predicted); Q3SXY8-2: 36795 Da (predicted); Q3SXY8-3: 37087 Da (predicted).
Sumoylation is required for PKD2 entry into cilium

Subunit：Monomer (By similarity)

RRID

AB_3719302

Synonyms

ADP ribosylation factor like 13B antibody; ADP ribosylation factor like 2 like 1 antibody; ADP-ribosylation factor-like protein 13B antibody; ADP-ribosylation factor-like protein 2-like 1 antibody; AR13B_HUMAN antibody; arl13b antibody; ARL2-like protein 1 antibody; ARL2L1 antibody; JBTS8 antibody

Documentation

Select Batch:

Data Sheet (231 KB) SDS (252 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)