BMPR1B Antibody
(Synonyms: CDw293, Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, BMPR1B)BMPR1B Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to BMPR1B.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
BMPR1B Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to BMPR1B.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 51 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 56; 60 kDa
Purified recombinant protein of human BMPR1B
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
BMPR1B is an On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction
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Subcellular Localization
Cell membrane
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Isoforms & Post-Translational Modification
BMPR1B has 2 isoforms, O00238-1: amino acid length is 502, molecular weight is 56930 Da (predicted); O00238-2: amino acid length is 532, molecular weight is 60582 Da (predicted).可发生自磷酸化BMPR1B 存在 2 个异构体，O00238-1：氨基酸个数为 502 个，分子量为 56930 Da (预测)；O00238-2：氨基酸个数为 532 个，分子量为 60582 Da (预测)。Autophosphorylated
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Subunit
Interacts with high affinity with GDF5; positively regulates chondrocyte differentiation.
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SwissProt ID
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Synonyms
CDw293, Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, BMPR1B
Documentation
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