C10orf63 Antibody (YA2894)
(Synonyms: C10orf63; ENKUR; Enkurin)C10orf63 Antibody (YA2894) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C10orf63.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
C10orf63 Antibody (YA2894) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C10orf63.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 29 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 29 kDa
Entrez Gene: 219670 Human ; 71233 Mouse ;
SwissProt: Q8TC29 Human ; Q6SP97 Mouse ;
OMIM: 611025 Human
A synthesized peptide derived from human C10orf63 aa1-180/256.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
C10orf63 is an Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating[1].
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Subcellular Localization
Cytoplasm, cytoskeleton, cilium axoneme; Cytoplasm, cytoskeleton, flagellum axoneme
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Expression
Tissue_specificity:Expressed in airway epithelial cells -
Subunit
Microtubule inner protein component of sperm flagellar doublet microtubules (By similarity). Binds calmodulin via its IQ domain. Interacts with TRPC1, TRPC2, TRPC5, but not TRPC3 (By similarity). Interacts with CFAP45 (PubMed:33139725)
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SwissProt ID
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Synonyms
C10orf63; ENKUR; Enkurin
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Research Field
Signal Transduction
Documentation
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