ENKUR - enkurin, TRPC channel interacting protein Gene

Also Known as CFAP106; C10orf63

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 219670

About ENKUR

Cytogenetic location: 10p12.1 Genomic coordinates (GRCh38): 10:24,981,985-25,062,327 (from NCBI)

This gene has 5 transcripts (splice variants), 230 orthologues and 1 paralogue. Biased expression in brain (RPKM 2.4), testis (RPKM 1.9) and 7 other tissues.

Summary

This gene encodes a protein that interacts with Calmodulin and several transient receptor potential canonical cation channel proteins. The encoded protein may function as an adaptor to localize signal transduction machinery to calcium channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

ENKUR Products (2)

mRNA	Protein	Name
NM_001270383.2	NP_001257312.1	enkurin isoform 2
NM_145010.4	NP_659447.1	enkurin isoform 1

ENKUR Protein Structure

Enkurin

0
100
200
256 a.a.

Protein Preferred Names	Protein Names
enkurin

ENKUR Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Références
Intra	ENKUR	Q8TC29	CFAP45	Homo sapiens	Q9UL16	Validated Y2H	32296183
Intra	ENKUR	Q8TC29	APBB2	Homo sapiens	Q92870-2	Y2H Array	32814053
Intra	ENKUR	Q8TC29	APBB2	Homo sapiens	Q92870-2	Validated Y2H	32814053
Intra	ENKUR	Q8TC29	APBB2	Homo sapiens	Q92870-2	Y2H Pooling	32814053
Intra	ENKUR	Q8TC29	DCTN1	Homo sapiens	Q14203-5	Validated Y2H	32814053
Intra	ENKUR	Q8TC29	DCTN1	Homo sapiens	Q14203-5	Y2H Pooling	32814053
Intra	ENKUR	Q8TC29	DCTN1	Homo sapiens	Q14203-5	Y2H Array	32814053
Intra	ENKUR	Q8TC29	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
Intra	ENKUR	Q8TC29	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
Intra	ENKUR	Q8TC29	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
Intra	ENKUR	Q8TC29	HTRA2	Homo sapiens	O43464	Y2H Array	32814053
Intra	ENKUR	Q8TC29	HTRA2	Homo sapiens	O43464	Validated Y2H	32814053
Intra	ENKUR	Q8TC29	HTRA2	Homo sapiens	O43464	Y2H Pooling	32814053
Intra	ENKUR	Q8TC29	UCHL1	Homo sapiens	P09936	Y2H Array	32814053
Intra	ENKUR	Q8TC29	UCHL1	Homo sapiens	P09936	Y2H Pooling	32814053
Intra	ENKUR	Q8TC29	UCHL1	Homo sapiens	P09936	Validated Y2H	32814053
Intra	ENKUR	Q8TC29	PRPH	Homo sapiens	P41219	Y2H Pooling	32814053
Intra	ENKUR	Q8TC29	PRPH	Homo sapiens	P41219	Validated Y2H	32814053
Intra	ENKUR	Q8TC29	PRPH	Homo sapiens	P41219	Y2H Array	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

ENKUR Anticorps

Cat. No.	Nom du produit	Application	Reactivity
HY-P83149	C10orf63 Antibody (YA2894)	WB	Human, Mouse

Related Diseases

Diseases	Alias
Cone-Rod Dystrophy 18	CORD18 Dystrophy, Cone-Rod, Type 18
Visceral Heterotaxy	Situs Ambiguus Heterotaxia Heterotaxy Syndrome Heterotaxy Lateralization Defect Situs Ambiguous Left Isomerism Htx Ivemark Syndrome Right Isomerism Situs Ambiguus Viscerum Incomplete Situs Inversus Partial Situs Inversus Heterotaxy, Visceral Asplenia Syndrome Bilateral Left-Sidedness Polysplenia Syndrome Moller Syndrome
Primary Ciliary Dyskinesia	Immotile Cilia Syndrome Kartagener Syndrome Dextrocardia Bronchiectasis And Sinusitis Pcd Ciliary Motility Disorders Ciliary Motility Disorder Immotile Ciliary Syndrome Ciliary Dyskinesia Primary Ics Polynesian Bronchiectasis Dextrocardia-Bronchiectasis-Sinusitis Syndrome Immotile Cilia Syndrome, Kartagener Type Primary Ciliary Dyskinesia And Situs Inversus Primary Ciliary Dyskinesia, Kartagener Type Siewert Syndrome Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-RS04377	ENKUR Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ENKUR	VGNC	VGNC:40365
Macaca mulatta	ENKUR	VGNC	VGNC:106045
Felis catus	ENKUR	VGNC	VGNC:83874
Bos taurus	ENKUR	VGNC	VGNC:28496
Rattus norvegicus	ENKUR	RGD	RGD:1309839
Mus musculus	ENKUR	MGD	MGI:1918483
Others	ENKUR	NCBI