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C14orf166 Antibody (YA7988)(PBS only)

(Synonyms: CGI-99; CGI99; CLE; CLE7; hCLE1; LCRP369; RLLM1)

C14orf166 Antibody (YA7988) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C14orf166.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB, IHC-P, ICC/IF

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • C14orf166 Antibody (YA7988)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:500-2000 1:100-200 1:100-250

Product Details

Description

C14orf166 Antibody (YA7988) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C14orf166.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 27.9 kDa
Immunogen

Full length human recombinant protein of human C14orf166 produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    C14orf166 is a RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex and is required for tRNA ligation. May be required for RNA transport |(Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication[1][2][3][4].

  • Subcellular Localization

    Nucleus,Cytoplasm, cytosol,Cytoplasm, perinuclear region,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,Nucleus,Cytoplasm

  • Expression


    Tissue_Specificity: Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in adult brain, adult lung, placenta, fetal liver and fetal kidney. Overexpressed in many brain tumors
    Induction: (Microbial infection) Up-regulated specifically following influenza A virus (IAV) infection in a viral replication-dependent manner (at protein level) (PubMed:26864902)

  • Isoforms & Post-Translational Modification

    Q9Y224: 244 amino acids, molecular weight 28068 Da.

  • Subunit

    Homodimer (Probable)

  • SwissProt ID

    Q9Y224

  • Synonyms

    CGI-99; CGI99; CLE; CLE7; hCLE1; LCRP369; RLLM1

C14orf166 Antibody (YA7988)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • C14orf166 Antibody (YA7988)(PBS only) Product Image