CD200R Antibody
(別名: Mox2r, Ox2r, Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, OX102 antigen)CD200R Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CD200R.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
CD200R Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CD200R.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 36; 75 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 36 kDa
Synthetic peptide corresponding to the C-term region of human CD200R.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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輸送条件
Shipping with blue ice.
Background
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Function
CD200R is an Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200
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Subcellular Localization
Cell membrane
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Expression
Tissue_Specificity: Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells. -
Isoforms & Post-Translational Modification
CD200R has 4 isoforms, Q8TD46-4: amino acid length is 348, molecular weight is 39041 Da (predicted); Q8TD46-1: amino acid length is 325, molecular weight is 36605 Da (predicted); Q8TD46-2: amino acid length is 188, molecular weight is 21291 Da (predicted); Q8TD46-3: amino acid length is 165, molecular weight is 18855 Da (predicted).CD200R 存在 4 个异构体，Q8TD46-4：氨基酸个数为 348 个，分子量为 39041 Da (预测)；Q8TD46-1：氨基酸个数为 325 个，分子量为 36605 Da (预测)；Q8TD46-2：氨基酸个数为 188 个，分子量为 21291 Da (预测)；Q8TD46-3：氨基酸个数为 165 个，分子量为 18855 Da (预测)。
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Subunit
CD200 and CD200R1 interact via their respective N-terminal Ig-like domains (By similarity).
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SwissProt ID
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別名
Mox2r, Ox2r, Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, OX102 antigen
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