CD42a Antibody (YA6500)
(Synonyms: CD42a antibody; Glycoprotein 9 antibody; Glycoprotein IX antibody; Glycoprotein IX (platelet) antibody; Glycoprotein IX precursor antibody; GP IX antibody; GP-IX antibody; GP9 antibody; GPIX antibody; GPIX_HUMAN antibody; CD42a antibody; Glycoprotein 9 antibody; Glycoprotein IX antibody; Glycoprotein IX (platelet) antibody; Glycoprotein IX precursor antibody; GP IX antibody; GP-IX antibody; GP9 antibody; GPIX antibody; GPIX_HUMAN antibody; Platelet glycoprotein IX antibody; )CD42a Antibody (YA6500) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD42a.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:2000 | 1:2000 |
Product Details
CD42a Antibody (YA6500) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD42a.
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Host Mouse
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 28 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 19 kDa
Recombinant protein within N-terminal human CD42a.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD42a is a platelet membrane glycoprotein encoded by the GP9 gene and is an important component of the GPIb-IX-V complex. CD42a is mainly expressed in platelets and megakaryocytes. Although it does not directly bind to vWF, it is crucial for the stable expression and normal function of the complex. CD42a participates in the initial adhesion of platelets to damaged blood vessel walls and is a key early molecule in the hemostatic response. CD42a is an important pathogenic protein associated with Bernard-Soulier syndrome and is also a commonly used biomarker in megakaryocyte differentiation, AML-M7 immunophenotyping, and platelet function testing.
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Subcellular Localization
Membrane
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Isoforms & Post-Translational Modification
CD42a: 177 amino acids, molecular weight 19046 Da.
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Subunit
Two GP-Ib beta are disulfide-linked to one GP-Ib alpha
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SwissProt ID
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Synonyms
CD42a antibody; Glycoprotein 9 antibody; Glycoprotein IX antibody; Glycoprotein IX (platelet) antibody; Glycoprotein IX precursor antibody; GP IX antibody; GP-IX antibody; GP9 antibody; GPIX antibody; GPIX_HUMAN antibody; CD42a antibody; Glycoprotein 9 antibody; Glycoprotein IX antibody; Glycoprotein IX (platelet) antibody; Glycoprotein IX precursor antibody; GP IX antibody; GP-IX antibody; GP9 antibody; GPIX antibody; GPIX_HUMAN antibody; Platelet glycoprotein IX antibody;
Documentation