2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. CD97 Antibody (YA1144)

CD97 Antibody (YA1144) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD97.

For research use only. We do not sell to patients.

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20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

CD97 Antibody (YA1144) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD97.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molecular Weight
Predicted band size: 92 kDa;
Observed band size: 75 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human CD97
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:200
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.145.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration
Subcellular Localization：Cell membrane; Multi-pass membrane protein; Secreted, extracellular space
Expression：
Tissue_specificity:CD97 is widely expressed in most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Smooth muscle cells also express CD97 in large quantities. Furthermore, CD97 is expressed in thyroid cancer, colorectal cancer, gastric cancer, esophageal cancer, and pancreatic cancer. CD97 expression is increased under the inflammatory conditions of the central nervous system in multiple sclerosis and in the synovial tissue of rheumatoid arthritis. Increased CD97 expression in the synovium is accompanied by elevated levels of detectable soluble CD97 in the synovial fluid.

Induction:Rapid up-regulation during lymphocyte activation
Isoforms & Post-Translational Modification：P48960 has 3 isomers: P48960-1: 91869 Da (predicted); P48960-2: 81743 Da (predicted); P48960-3: 86628 Da (predicted).
Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit
Subunit：Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Interacts with complement decay-accelerating factor (DAF). The largest isoform (isoform 1) interacts with chondroitin sulfate
Database

Entrez Gene: 976 Human

SwissProt: P48960 Human

OMIM: 601211 Human

Research Field

Neuroscience
Synonyms
ADGRE5; Adhesion G protein-coupled receptor E5; CD97 antigen; Leukocyte antigen CD97; Seven span transmembrane protein; TM7LN1
Documentation
User Guide for Antibodies (1077 KB)

CD97 Antibody (YA1144) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD97 Antibody (YA1144)
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HY-P81399
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