LIG1 Antibody (YA1790)
(Synonyms: LIG1; DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1)LIG1 Antibody (YA1790) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LIG1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50-1:200 |
Product Details
LIG1 Antibody (YA1790) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LIG1.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 140 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 102 kDa
A synthesized peptide derived from human DNA Ligase I aa30-85/919.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LIG1 is a DNA ligase that seals nicks in double-stranded during DNA repair. Also involved in DNA replication and DNA recombination[1].
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
P18858 has 3 isomers: P18858-1: 101736 Da (predicted); P18858-2: 88516 Da (predicted); P18858-3: 98228 Da (predicted).
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Subunit
Interacts with PCNA (PubMed:24911150). Interacts with POLB (PubMed:19336415)
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SwissProt ID
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Synonyms
LIG1; DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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