Factor VII Antibody
(Synonyms: Coagulation factor VII, Proconvertin, Serum prothrombin conversion accelerator, SPCA, F7)
Based on 1 Customer Validation
Factor VII Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Factor VII.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:50-200 |
Product Details
Factor VII Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Factor VII.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 51 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 51 kDa
Synthetic peptide corresponding to the N-term region of human Factor VII.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Factor VII is an Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium[1].
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Plasma. -
Isoforms & Post-Translational Modification
Factor VII has 2 isoforms, P08709-1: amino acid length is 466, molecular weight is 51594 Da (predicted); P08709-2: amino acid length is 444, molecular weight is 49320 Da (predicted).部分谷氨酸残基发生的维生素 K 依赖性酶促羧化修饰，使修饰后的蛋白能够结合钙离子Factor VII 存在 2 个异构体，P08709-1：氨基酸个数为 466 个，分子量为 51594 Da (预测)；P08709-2：氨基酸个数为 444 个，分子量为 49320 Da (预测)。The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium
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Subunit
Heterodimer of a light chain and a heavy chain linked by a disulfide bond.
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SwissProt ID
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Synonyms
Coagulation factor VII, Proconvertin, Serum prothrombin conversion accelerator, SPCA, F7
Documentation
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