2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. FDPS Antibody (YA2817)

FDPS Antibody (YA2817) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FDPS.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

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  • Descripciòn

  • Referencias

Descripciòn

FDPS Antibody (YA2817) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FDPS.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Peso molecular
Predicted band size: 48 kDa;
Observed band size: 48 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Hamster
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human FDPS
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
Sensitivity Endogenous Pureza Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Verification Image
WB

  • Western blot analysis of extracts from HepG2 (lane 2(20μg), Hela (lane 3(20μg), THP-1 (lane 4(20μg), using FDPS Antibody. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in TBST for 2 hour at room temperature. The primary antibody and Loading control antibody (Beta Actin, HY-P80438, 1/3000) was used in 5% BSA in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (HY-P8004/HY-P8001, 1/10,000) was used for 1 hour at room temperature.

Background
Function：Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate
Subcellular Localization：Cytoplasm
Isoforms & Post-Translational Modification：P14324 has 2 isomers: P14324-1: 48275 Da (predicted); P14324-2: 40532 Da (predicted).
Subunit：Homodimer. Interacts with RSAD2
RRID
Database

Entrez Gene: 2224 Human

SwissProt: P14324 Human ;

OMIM: 616631 Human

Research Field

Cardiovascular
Synonyms
FPS; FPPS; POROK9
Documentación
SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)
Referencias

FDPS Antibody (YA2817) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
FDPS Antibody (YA2817)
Cat. No.:
HY-P83072
Cantidad:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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