FHL2 Antibody (YA1875)

Cat. No.: HY-P82130: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

FHL2 Antibody (YA1875) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FHL2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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FHL2 Antibody (YA1875) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

FHL2 Antibody (YA1875) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FHL2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 32 kDa;

Observed band size: 32 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q14192

Gene ID

2274 [NCBI]

Immunogen

A synthesized peptide derived from human FHL2 aa20-279.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:20

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:28717008)

Subcellular Localization：Cytoplasm; Nucleus; Cytoplasm, myofibril, sarcomere, Z line

Expression：
Tissue_specificity:Expressed in skeletal muscle and heart

Isoforms & Post-Translational Modification：Q14192 has 2 isomers: Q14192-1: 32193 Da (predicted); Q14192-2: 15890 Da (predicted).

Subunit：Interacts with ZNF638 and TTN/titin (PubMed:11813260, PubMed:12432079). Interacts with E4F1 (PubMed:16652157). Interacts with GRB7 (PubMed:18853468).

Database

Entrez Gene: 2274 Human ; 14200 Mouse ; 63839 Rat

SwissProt: Q14192 Human ; O70433 Mouse ; O35115 Rat

OMIM: 602633 Human

Research Field

Epigenetics and Nuclear Signaling

Synonyms

AAG11; DRAL; Fhl2; SLIM3

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

FHL2 Antibody (YA1875) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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FHL2 Antibody (YA1875)

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Product Detail

Background

Documentation

FHL2 Antibody (YA1875) Related Classifications

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