Flotillin 2 Antibody (YA1439)
(Synonyms: epidermal surface antigen; ESA; flotillin-2; Membrane component chromosome 17 surface marker 1; ESA1; M17S1)Flotillin 2 Antibody (YA1439) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Flotillin 2.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IP
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
|
IP
IP: Immunoprecipitation
|
|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:30 |
Product Details
Flotillin 2 Antibody (YA1439) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Flotillin 2.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 47 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 47 kDa
Entrez Gene: 2319 Human ; 14252 Mouse ; 83764 Rat
SwissProt: Q14254 Human ; Q60634 Mouse ; Q9Z2S9 Rat
OMIM: 131560 Human
A synthesized peptide derived from human Flotillin 2 aa324-366.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Flotillin 2 may act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function
-
Subcellular Localization
Cell membrane; Peripheral membrane protein; Membrane, caveola; Peripheral membrane protein; Endosome; Membrane; Lipid-anchor
-
Expression
Tissue_specificity:In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes -
Subunit
Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2 (By similarity). Interacts with ECPAS
-
SwissProt ID
-
Synonyms
epidermal surface antigen; ESA; flotillin-2; Membrane component chromosome 17 surface marker 1; ESA1; M17S1
-
Research Field
Neuroscience
Documentation