FOXP2 Antibody (YA3528)(PBS only)

Cat. No.: HY-P83831A: Data Sheet User Guide for Antibodies
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FOXP2 Antibody (YA3528) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FOXP2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

FOXP2 Antibody (YA3528) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FOXP2.

Host

Mouse

Molecular Weight

Predicted band size: 80 kDa;

Observed band size: 70-80 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O15409

Gene ID

93986 [NCBI]

Immunogen

Purified recombinant fragment of human FOXP2 (AA: 641-740) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:Isomer 1 and isomer 6 are expressed in the human brain, caudate nucleus, and lungs.

Isoforms & Post-Translational Modification：O15409 has 9 isomers: O15409-1: 79919 Da (predicted); O15409-3: Da (predicted); O15409-2: 70104 Da (predicted); O15409-4: 82565 Da (predicted); O15409-5: 18315 Da (predicted); O15409-6: 48764 Da (predicted); O15409-7: 40969 Da (predicted); O15409-8: 9377 Da (predicted); O15409-9: 81840 Da (predicted).

Subunit：Forms homodimers and heterodimers with FOXP1 and FOXP4. Isoform 1 and isoform 3 interact with TBR1 (PubMed:25232744, PubMed:30250039). Interacts with ZMYM2 (PubMed:32891193)

Synonyms

SPCH1; CAGH44; TNRC10

Documentation

User Guide for Antibodies (1077 KB)