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Glucose-6-phosphate isomerase Antibody (YA3675)(PBS only)

(Synonyms: AMF; NLK; PGI; PHI; GNPI; SA-36; GPI)

Glucose-6-phosphate isomerase Antibody (YA3675) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Glucose-6-phosphate isomerase.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, ICC/IF, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • Glucose-6-phosphate isomerase Antibody (YA3675)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:1000 1:200-1:1000 1:10000

Product Details

Description

Glucose-6-phosphate isomerase Antibody (YA3675) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Glucose-6-phosphate isomerase.

  • Host Mouse
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 63 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 63 kDa
Immunogen

Purified recombinant fragment of human GPI aa 1-558.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Glucose-6-phosphate isomerase is an In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion[1][2][3][4].

  • Subcellular Localization

    Cytoplasm; Secreted

  • Subunit

    Homodimer; in the catalytically active form (PubMed:11371164, PubMed:12054796, PubMed:12777791). Monomer in the secreted form (PubMed:11371164, PubMed:12054796, PubMed:12777791)

  • SwissProt ID

    P06744

  • Gene ID
    2821 [NCBI]
  • Synonyms

    AMF; NLK; PGI; PHI; GNPI; SA-36; GPI

Glucose-6-phosphate isomerase Antibody (YA3675)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • Glucose-6-phosphate isomerase Antibody (YA3675)(PBS only) Product Image