Glycodelin Antibody (YA2193)

Cat. No.: HY-P82448: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

Glycodelin Antibody (YA2193) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glycodelin.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Glycodelin Antibody (YA2193) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Glycodelin Antibody (YA2193) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glycodelin.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 21 kDa;

Observed band size: 24 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P09466

Gene ID

5047 [NCBI]

Immunogen

A synthesized peptide derived from human Placental Protein 14 / PAEP aa130-180/180.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 50 mM Tris-Glycine(pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:7531163, PubMed:9918684). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155)

Subcellular Localization：Secreted

Expression：
Tissue_specificity:This protein is, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy (PubMed:3667877) . Glycodelin-A is expressed in amniotic fluid, endometrium/decidua and maternal serum (at protein level) (PubMed:3194393) . Glycodelin-F is expressed in follicular fluid, luteinized granulosa cells and the oviduct (at protein level) (PubMed:12672671) . Glycodelin-S is expressed in seminal plasma and seminal vesicles (at protein level) (PubMed:9239694) . Glycodelin-C is detected in cumulus cells (at protein level) , but cumulus cells do not synthesize Glycodelin-C but take up and convert glycodelin-A and -F vis glycan remodeling (PubMed:17192260)

Isoforms & Post-Translational Modification：P09466 has 3 isomers: P09466-1: 20624 Da (predicted); P09466-2: 18279 Da (predicted); P09466-3: 9953 Da (predicted).
Four distinct glycoforms A, C, F and S arise from different N-linked oligosaccharide chains at amino acid residues Asn-46 and Asn-81. Glycodelin-A and -F are taken up by the cumulus cells in which partial deglycosylation takes place to produce glycodelin-C

Subunit：Homodimer (PubMed:25422905, PubMed:9239694)

Database

Entrez Gene: 5047 Human

SwissProt: P09466 Human

OMIM: 173310 Human

Research Field

Tags & Cell Markers

Synonyms

GdA; GdF; GdS; Glycodelin A; Glycodelin; Glycodelin F; Glycodelin S; PAEG; PAEP; PEG; PEP; Placental protein 14; PP14

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Glycodelin Antibody (YA2193) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Glycodelin Antibody (YA2193)

Glycodelin Antibody (YA2193) Featured Recommendations:

Product Detail

Background

Documentation

Glycodelin Antibody (YA2193) Related Classifications

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