GRIK3 Antibody (YA4222)(PBS only)

Cat. No.: HY-P84525A: Data Sheet User Guide for Antibodies
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GRIK3 Antibody (YA4222) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GRIK3.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

GRIK3 Antibody (YA4222) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GRIK3.

Host

Mouse

Molecular Weight

Predicted band size: 104 kDa;

Observed band size: 104 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q13003

Gene ID

2899 [NCBI]

Immunogen

Purified recombinant fragment of human GRIK3 (AA: extra 32-173) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:7719709). In association with GRIK2, involved in presynaptic facilitation of glutamate release at hippocampal mossy fiber synapses (By similarity)

Subcellular Localization：Cell membrane; Multi-pass membrane protein; Postsynaptic cell membrane; Multi-pass membrane protein

Subunit：Homotetramer, and heterotetramer with either GRIK4 or GRIK5. Can form functional heteromeric receptors with GRIK2. Interacts with PRKCABP. Interacts with NETO2

Synonyms

EAA5; GLR7; GLUR7; GluK3; GluR7a

Documentation

User Guide for Antibodies (1077 KB)