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  5. Histone H2B (mono methyl R79) Antibody (YA376)

Histone H2B (mono methyl R79) Antibody (YA376)

Cat. No.: HY-P80165
User Guide for Antibodies Technical Support

Histone H2B (mono methyl R79) Antibody (YA376) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2B (mono methyl R79).

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사이즈 가격 재고
20 μL Ask For Quote & Lead Time
50 μL Ask For Quote & Lead Time
100 μL Ask For Quote & Lead Time

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

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  • 제품 설명

제품 설명

Histone H2B (mono methyl R79) Antibody (YA376) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2B (mono methyl R79).
Host

Rabbit
Clonality

Recombinant, Monoclonal
분자량
Predicted band size: 14 kDa;
Observed band size: 14 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse
SwissProt ID
Gene ID
Immunogen

Synthetic peptide corresponding to Human Histone H2B.AA range:51-100.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:200
Sensitivity Endogenous Purity Protein A affinity purified.
Conjugation Non-conjugated Modification Methylated
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
선적

Shipping with blue ice.
Background
Function：Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling; Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid
Subcellular Localization：Nucleus; Chromosome
Subunit：The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Heterodimer H2BC11 and H2AZ1 interacts with VPS72 (via N-terminal domain) (PubMed:26974126)
Database

Entrez Gene: 337874 Human ; 54145 Human ; 8349 Human ; 104021 Mouse ; 64647 Rat

SwissProt: O60814 Human ; P06899 Human ; P23527 Human ; P33778 Human ; P57053 Human ; P58876 Human ; P62807 Human ; Q16778 Human ; Q5QNW6 Human ; Q8N257 Human ; Q93079 Human ; Q99877 Human ; Q99879 Human ; Q99880 Human ; P10854 Mouse ; Q64475 Mouse ; Q00729 Rat

OMIM: 615045 Human

Research Field

Epigenetics and Nuclear Signaling
각종 서류
User Guide for Antibodies (1077 KB)

Histone H2B (mono methyl R79) Antibody (YA376) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Histone H2B (mono methyl R79) Antibody (YA376)
Cat. No.:
HY-P80165
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