Histone H2B (mono methyl R79) Antibody (YA376)
Histone H2B (mono methyl R79) Antibody (YA376) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2B (mono methyl R79).
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:50-1:200 | 1:50-1:200 |
Product Details
Histone H2B (mono methyl R79) Antibody (YA376) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2B (mono methyl R79).
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 14 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 14 kDa
Entrez Gene: 337874 Human ; 54145 Human ; 8349 Human ; 104021 Mouse ; 64647 Rat
SwissProt: O60814 Human ; P06899 Human ; P23527 Human ; P33778 Human ; P57053 Human ; P58876 Human ; P62807 Human ; Q16778 Human ; Q5QNW6 Human ; Q8N257 Human ; Q93079 Human ; Q99877 Human ; Q99879 Human ; Q99880 Human ; P10854 Mouse ; Q64475 Mouse ; Q00729 Rat
OMIM: 615045 Human
Synthetic peptide corresponding to Human Histone H2B.AA range:51-100.
Endogenous
Protein A affinity purified.
Non-conjugated
Methylated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Histone H2B core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling; Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid
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Subcellular Localization
Nucleus; Chromosome
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Subunit
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Heterodimer H2BC11 and H2AZ1 interacts with VPS72 (via N-terminal domain) (PubMed:26974126)
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SwissProt ID
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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