KDM4C Antibody (YA8589)(PBS only)

Cat. No.: HY-P88905A: Data Sheet User Guide for Antibodies
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KDM4C Antibody (YA8589) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KDM4C.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

KDM4C Antibody (YA8589) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KDM4C.

Host

Mouse

Molecular Weight

Predicted band size: 120.0 kDa

Species Reactivity

Human, Rat

SwissProt ID

Q9H3R0

Immunogen

Full-length protein expressed in 293T cell transfected with human KDM4C expression vector

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-250
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate

Subcellular Localization：Nucleus

Expression：
Tissue_Specificity: Overexpressed in several esophageal squamous cell carcinomas (ESCs)

Isoforms & Post-Translational Modification：Q9H3R0 has four isomers: Q9H3R0-1: 119982 Da (predicted); Q9H3R0-2: 118416 Da (predicted); Q9H3R0-3: 91891 Da (predicted); Q9H3R0-4: 94376 Da (predicted).

Synonyms

GASC1; JHDM3C; JMJD2C; TDRD14C

Documentation

User Guide for Antibodies (1077 KB)