KSHV ORF62 Antibody (YA4942)
KSHV ORF62 Antibody (YA4942) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to KSHV ORF62.
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Host:
Mouse
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Isotype:
IgM
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Application:
IHC-P, ELISA
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Reactivity :
KSHV
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Formulation:
Supplied in Asciticfluidcontaining0.03%sodiumazide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
KSHV ORF62 Antibody (YA4942) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to KSHV ORF62.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityKSHV
Purified recombinant fragment of humanKSHVORF62 expressedin E.Coli. The exact sequence is proprietary to MCE.
Endogenous
affinity purified
Non-conjugated
Unmodified
IgM
Product Properties
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Appearance
Liquid
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Formulation
Supplied in Asciticfluidcontaining0.03%sodiumazide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KSHV ORF62 receptor that signals constitutively via several signaling pathways including PI3K/AKT as well as mitogen- and stress-activated/MAP kinases. Promotes host cell proliferation and survival, modulates cell migration, stimulates angiogenesis, and recruits inflammatory cells, both in expressing cells and in neighboring cells. Maintains chronic activation of NF-kappa-B via interaction with host CADM1[1].
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Subcellular Localization
Host cell membrane; Multi-pass membrane protein
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Subunit
Interacts with protein K7; this interaction promotes vGPCR proteasomal degradation (PubMed:18802460). Interacts with host CADM1; this interaction is essential for chronic NF-kappa-B activation (PubMed:29698475)
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SwissProt ID
Documentation
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