LOH12CR1 Antibody (YA8632)
(Synonyms: LOH1CR12)LOH12CR1 Antibody (YA8632) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to LOH12CR1.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
ICC/IF
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|
| Dilution Ratio | 1:100-250 |
Product Details
LOH12CR1 Antibody (YA8632) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to LOH12CR1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 22 kDa
Full length human recombinant protein of human LOH12CR1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LOH12CR1 is an As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility
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Subcellular Localization
Lysosome membrane
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Expression
Tissue_Specificity: Ubiquitously expressed (at protein level) -
Isoforms & Post-Translational Modification
Q969J3 has two isomers: Q969J3-1: 22222 Da (predicted); Q969J3-2: 17000 Da (predicted).
Myristoylation at Gly-2 mediates attachment to lysosome membranes -
Subunit
Component of the BLOC-one-related complex (BORC) which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN (PubMed:25898167)
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SwissProt ID
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Synonyms
LOH1CR12
Documentation
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