M6PR Antibody (YA3870)(PBS only)

Cat. No.: HY-P84173A: Data Sheet User Guide for Antibodies
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M6PR Antibody (YA3870) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to M6PR.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

M6PR Antibody (YA3870) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to M6PR.

Host

Mouse

Molecular Weight

Predicted band size: 31 kDa;

Observed band size: 42 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

P20645

Gene ID

4074 [NCBI]

Immunogen

Purified recombinant fragment of human M6PR (AA: 124-277) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex

Subcellular Localization：Lysosome membrane; Single-pass type I membrane protein

Subunit：Homodimer. Binds GGA1, GGA2 and GGA3

Synonyms

SMPR; MPR46; CD-MPR; MPR 46; MPR-46; CD-M6PR

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/huvec-cell.html [Content Brief]