MAPK4 Antibody (YA8600)

Cat. No.: HY-P88916: Ficha de datos User Guide for Antibodies
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MAPK4 Antibody (YA8600) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MAPK4.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

MAPK4 Antibody (YA8600) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MAPK4.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 65.7 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P31152

Immunogen

Full length human recombinant protein of human MAPK4 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity)

Subcellular Localization：Cytoplasm,Nucleus

Expression：
Tissue_Specificity: High expression in heart and brain

Isoforms & Post-Translational Modification：P31152: 587 amino acids, molecular weight 65922 Da.

Subunit：Homodimer

Synonyms

ERK-4; ERK4; p63-MAPK; p63MAPK; PRKM4

Documentación

User Guide for Antibodies (1077 KB)