MAPK4 Antibody (YA8600)
(Synonyms: ERK-4; ERK4; p63-MAPK; p63MAPK; PRKM4)MAPK4 Antibody (YA8600) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MAPK4.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
MAPK4 Antibody (YA8600) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MAPK4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 65.7 kDa
Full length human recombinant protein of human MAPK4 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MAPK4 is an Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle
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Subcellular Localization
Cytoplasm,Nucleus
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Expression
Tissue_Specificity: High expression in heart and brain -
Isoforms & Post-Translational Modification
P31152: 587 amino acids, molecular weight 65922 Da.
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Subunit
Homodimer
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SwissProt ID
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Synonyms
ERK-4; ERK4; p63-MAPK; p63MAPK; PRKM4
Documentation