MAPK4 Antibody (YA8600)

(Synonyms: ERK-4; ERK4; p63-MAPK; p63MAPK; PRKM4)

MAPK4 Antibody (YA8600) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MAPK4.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    IHC-P, ICC/IF

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:150-500 1:100-250

Product Details

Description

MAPK4 Antibody (YA8600) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MAPK4.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 65.7 kDa
Immunogen

Full length human recombinant protein of human MAPK4 produced in HEK293T cell.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MAPK4 is an Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle

  • Subcellular Localization

    Cytoplasm,Nucleus

  • Expression


    Tissue_Specificity: High expression in heart and brain

  • Isoforms & Post-Translational Modification

    P31152: 587 amino acids, molecular weight 65922 Da.

  • Subunit

    Homodimer

  • SwissProt ID

    P31152

  • Synonyms

    ERK-4; ERK4; p63-MAPK; p63MAPK; PRKM4

MAPK4 Antibody (YA8600) Related Classifications

MOQ
Minimum order quantity
100 mg

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