NPEPPS/PSA Antibody
(Synonyms: PSA, NPEPPS, Puromycin-sensitive aminopeptidase, Cytosol alanyl aminopeptidase, AAP-S)NPEPPS Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to NPEPPS.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:1000-2000 |
Product Details
NPEPPS Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to NPEPPS.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 107 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 103 kDa
Synthetic peptide corresponding to the Central region of human NPEPPS.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NPEPPS/PSA is an Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain
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Subcellular Localization
Cytoplasm, cytosol; Nucleus
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Expression
Tissue_Specificity: Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level). -
Isoforms & Post-Translational Modification
NPEPPS/PSA has 2 isoforms, P55786-1: amino acid length is 919, molecular weight is 103276 Da (predicted); P55786-2: amino acid length is 839, molecular weight is 94516 Da (predicted).
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Subunit
Monomer
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SwissProt ID
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Synonyms
PSA, NPEPPS, Puromycin-sensitive aminopeptidase, Cytosol alanyl aminopeptidase, AAP-S
Documentation
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