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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. NRG3 Antibody (YA1432)

NRG3 Antibody (YA1432) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NRG3.

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사이즈 가격 재고 수량
20 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   견적 받기  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

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제품 설명

NRG3 Antibody (YA1432) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NRG3.
Host

Rabbit
Clonality

Recombinant, Monoclonal
분자량
Predicted band size: 78 kDa;
Observed band size: 55 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Rat
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human NRG3
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
선적

Shipping with blue ice.
Background
Function：Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes
Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Secreted; Cell membrane; Single-pass type I membrane protein
Expression：
Tissue_specificity:Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes
Isoforms & Post-Translational Modification：P56975 has 4 isomers: P56975-1: 77901 Da (predicted); P56975-2: 77164 Da (predicted); P56975-3: 56034 Da (predicted); P56975-4: 75031 Da (predicted).
Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form;Extensive glycosylation precedes the proteolytic cleavage (By similarity). Isoform 3 is glycosylated
Subunit：Interacts with ERBB4
Database

Entrez Gene: 10718 Human ; 18183 Mouse ; 498596 Rat

SwissProt: P56975 Human ; O35181 Mouse ;

OMIM: 605533 Human

Research Field

Neuroscience
Synonyms
NRG3; Pro-neuregulin-3; membrane-bound isoform; Pro-NRG3
각종 서류
User Guide for Antibodies (1077 KB)

NRG3 Antibody (YA1432) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
NRG3 Antibody (YA1432)
Cat. No.:
HY-P81687
수량:
MCE Japan Authorized Agent:

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