NRG3 Antibody (YA1432)

製品番号: HY-P81687: データシート User Guide for Antibodies
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NRG3 Antibody (YA1432) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NRG3.

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容量	価格（税別）	在庫状況	数量
20 μL	$146	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	$222	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	$360	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

Synthetic products have potential research and development risk.

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* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

NRG3 Antibody (YA1432) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NRG3.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 78 kDa;

Observed band size: 55 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

P56975

Gene ID

10718 [NCBI]

Immunogen

A synthetic peptide of human NRG3

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	純度	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes

Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Secreted; Cell membrane; Single-pass type I membrane protein

Expression：
Tissue_specificity:Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes

Isoforms & Post-Translational Modification：P56975 has 4 isomers: P56975-1: 77901 Da (predicted); P56975-2: 77164 Da (predicted); P56975-3: 56034 Da (predicted); P56975-4: 75031 Da (predicted).
Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form;Extensive glycosylation precedes the proteolytic cleavage (By similarity). Isoform 3 is glycosylated

Subunit：Interacts with ERBB4

Database

Entrez Gene: 10718 Human ; 18183 Mouse ; 498596 Rat

SwissProt: P56975 Human ; O35181 Mouse ;

OMIM: 605533 Human

Research Field

Neuroscience

Synonyms

NRG3; Pro-neuregulin-3; membrane-bound isoform; Pro-NRG3

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/t-cell-cell.html [Content Brief]