PACSIN3 Antibody (YA2540)
(Synonyms: SDPIII)PACSIN3 Antibody (YA2540) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PACSIN3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-F, IHC-P, ICC/IF, IP
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Reactivity :
Human
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50-1:100 | 1:50-1:200 | 1:20 |
Product Details
PACSIN3 Antibody (YA2540) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PACSIN3.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 48 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 48 kDa
A synthetic peptide of human PACSIN3 aa1-14.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PACSIN3 plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity
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Subcellular Localization
Cytoplasm; Cell membrane; Peripheral membrane protein; Cytoplasmic side
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Expression
Tissue_specificity:This gene is widely expressed in various tissues, with the highest concentrations in the heart and skeletal muscle, moderate concentrations in the placenta, liver, and pancreas, and extremely low concentrations in the brain, lungs, and kidneys. -
Subunit
Homodimer. May form heterooligomers with other PACSINs.
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SwissProt ID
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Synonyms
SDPIII
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Research Field
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Documentation
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