PAX3 Antibody (YA3896)(PBS only)

Cat. No.: HY-P84199A: Data Sheet User Guide for Antibodies
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PAX3 Antibody (YA3896) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PAX3.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PAX3 Antibody (YA3896) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PAX3.

Host

Mouse

Molecular Weight

Predicted band size: 53 kDa;

Observed band size: 56-60 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

P23760

Gene ID

5077 [NCBI]

Immunogen

Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10 (PubMed:21965087)

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：P23760 has 8 isomers: P23760-1: 52968 Da (predicted); P23760-2: 24136 Da (predicted); P23760-3: 22743 Da (predicted); P23760-4: 44822 Da (predicted); P23760-5: 45217 Da (predicted); P23760-6: 53336 Da (predicted); P23760-7: 53464 Da (predicted); P23760-8: 55975 Da (predicted).

Subunit：Can bind to DNA as a homodimer or a heterodimer with PAX7. Interacts with PAXBP1; the interaction links PAX3 to a WDR5-containing histone methyltransferase complex. Interacts with DAXX. Interacts with TBX18. Interacts with SOX10 (PubMed:21965087)

Synonyms

WS1; WS3; CDHS; HUP2

Documentation

User Guide for Antibodies (1077 KB)