PCB Antibody (YA2060)

Cat. No.: HY-P82315: Ficha de datos COA
SDS
User Guide for Antibodies
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PCB Antibody (YA2060) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PCB.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño	Stock	Cantidad
20 μL	En stock	Estimated Time of Arrival: December 31
50 μL	En stock	Estimated Time of Arrival: December 31
100 μL	En stock	Estimated Time of Arrival: December 31
250 μL	Obtener un presupuesto

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PCB Antibody (YA2060) Recomendaciones destacadas:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

PCB Antibody (YA2060) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PCB.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Peso molecular

Predicted band size: 130 kDa;

Observed band size: 130 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P11498

Gene ID

5091 [NCBI]

Immunogen

A synthesized peptide derived from human PCB aa7-64.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	Pureza	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate

Subcellular Localization：Mitochondrion matrix

Isoforms & Post-Translational Modification：P11498 has 2 isomers: P11498-1: 129634 Da (predicted); P11498-2: 57925 Da (predicted).
Acetylation of Lys-748 might play a role in catalytic activity regulation

Subunit：Homotetramer (PubMed:18297087). Interacts (via the biotin carboxylation domain) with SIRT4 (PubMed:23438705)

Database

Entrez Gene: 5091 Human ; 25104 Rat

SwissProt: P11498 Human ; Q05920 Mouse ; P52873 Rat

OMIM: 266150 Human

Research Field

Signal Transduction

Synonyms

PC; Pyruvate carboxylase; mitochondrial; Pyruvic carboxylase; PCB

Documentación

Select Batch:

Ficha de datos (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

PCB Antibody (YA2060) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PCB Antibody (YA2060)

PCB Antibody (YA2060) Recomendaciones destacadas:

Product Detail

Background

Descripciòn

PCB Antibody (YA2060) Related Classifications

Productos vistos recientemente:

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