Phospho-ErbB-3 (Tyr1289) Antibody (YA7597)

製品番号: HY-P87912: データシート SDS COA User Guide for Antibodies
FAQs
Technical Support

Phospho-ErbB-3 (Tyr1289) Antibody (YA7597) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Phospho-ErbB-3 (Tyr1289).

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況	数量
20 μL	$118	在庫あり	Estimated Time of Arrival: December 31
50 μL	$185	在庫あり	Estimated Time of Arrival: December 31
100 μL	$300	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

Phospho-ErbB-3 (Tyr1289) Antibody (YA7597) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Phospho-ErbB-3 (Tyr1289).

Host

Rabbit

Clonality

Monoclonal,Recombinant

分子量

Predicted band size: 148 kDa;

Observed band size: 185 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P21860

Immunogen

The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
WB WB: Western Blot	1:2000-1:10000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:5000-1:20000
IP IP: Immunoprecipitation	1:50-1:200

Sensitivity	Endogenous	純度	Protein A affinity purified
Conjugation	Non-conjugated	Modification	Phosphorylated
Isotype	IgG, Kappa

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908)

Subcellular Localization：Cell membrane,Secreted

Expression：
Tissue_Specificity: Epithelial tissues and brain

Isoforms & Post-Translational Modification：P21860 has 5 isomers: P21860-1: 148098 Da (predicted); P21860-2: 20136 Da (predicted); P21860-3: 36490 Da (predicted); P21860-4: 141752 Da (predicted); P21860-5: 77426 Da (predicted).
Autophosphorylated (PubMed:20351256)

Subunit：Monomer and homodimer

ドキュメンテーション

Select Batch:

データシート (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Phospho-ErbB-3 (Tyr1289) Antibody (YA7597) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-ErbB-3 (Tyr1289) Antibody (YA7597)

Product Detail

Background

説明

Phospho-ErbB-3 (Tyr1289) Antibody (YA7597) 関連分類

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