Phospho-GATA3 (Ser308) Antibody (YA2593)(PBS only)

Cat. No.: HY-P82848A: Data Sheet User Guide for Antibodies
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Phospho-GATA3 (Ser308) Antibody (YA2593) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GATA3 (Ser308).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Phospho-GATA3 (Ser308) Antibody (YA2593) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GATA3 (Ser308).

Host

Rabbit

분자량

Predicted band size: 48 kDa;

Observed band size: 48 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P23771

Gene ID

2625 [NCBI]

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser308 of human GATA3

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:T cells and endothelial cells

Isoforms & Post-Translational Modification：P23771 has 2 isomers: P23771-1: 47916 Da (predicted); P23771-2: 48045 Da (predicted).

Subunit：Interacts with TBX21 ('Tyr-530' phosphorylated form)

Research Field

Immunology

Synonyms

GATA3; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3

각종 서류

User Guide for Antibodies (1077 KB)