Phospho-GATA3 (Ser308) Antibody (YA2593)(PBS only)

製品番号: HY-P82848A: データシート User Guide for Antibodies
FAQs
Technical Support

Phospho-GATA3 (Ser308) Antibody (YA2593) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GATA3 (Ser308).

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

Phospho-GATA3 (Ser308) Antibody (YA2593) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-GATA3 (Ser308).

Host

Rabbit

分子量

Predicted band size: 48 kDa;

Observed band size: 48 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P23771

Gene ID

2625 [NCBI]

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser308 of human GATA3

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IP IP: Immunoprecipitation	1:20

純度	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:T cells and endothelial cells

Isoforms & Post-Translational Modification：P23771 has 2 isomers: P23771-1: 47916 Da (predicted); P23771-2: 48045 Da (predicted).

Subunit：Interacts with TBX21 ('Tyr-530' phosphorylated form)

Research Field

Immunology

Synonyms

GATA3; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3

ドキュメンテーション

User Guide for Antibodies (1077 KB)

Phospho-GATA3 (Ser308) Antibody (YA2593)(PBS only) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-GATA3 (Ser308) Antibody (YA2593)(PBS only)

Product Detail

Background

説明

Phospho-GATA3 (Ser308) Antibody (YA2593)(PBS only) 関連分類

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