Phospho-TrkA/B (Tyr490/Tyr516) Antibody

Cat. No.: HY-P80862: FAQs
Data Sheet User Guide for Antibodies

Phospho-TrkA/B (Tyr490/Tyr516) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 92 kDa, targeting to Phospho-TrkA/B (Tyr490/Tyr516). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size	Price	Stock
10 μL	$70	Ask For Quote & Lead Time
50 μL	$185	Ask For Quote & Lead Time
100 μL	$300	Ask For Quote & Lead Time

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Biological Activity
Technical Parameters
Properties
Documentation

Description	Phospho-TrkA/B (Tyr490/Tyr516) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 92 kDa, targeting to Phospho-TrkA/B (Tyr490/Tyr516). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.
Background	TrkA/B: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Tag	Free
Gene ID	4915
Synonyms	NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B
Molecular Weight	Predicted band size: 92 kDa
Purity	affinity purified
Conjugation	Non-conjugated
Research Field	Neuroscience
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Host	Rabbit
Reactivity	Human, Mouse, Rat
SwissProt ID	Q16620
Dilution Ratio	WB: 1:500-1:1,000
Application	WB
Appearance	Liquid
Formulation	Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Immunogen	Synthetic phosphopeptide corresponding to residues surrounding Tyr516 of Human TrkB.The exact sequence is proprietary to MCE.
Documentation	Data Sheet (232 KB) User Guide for Antibodies (1077 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-TrkA/B (Tyr490/Tyr516) Antibody

Biological Activity

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Documentation

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