Phospho-VAV1 (Tyr174) Antibody (YA10030)
(Synonyms: VAV, VAV1, Proto-oncogene vav)Phospho-VAV1 (Tyr174) Antibody (YA10030) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to Phospho-VAV1 (Tyr174).
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, ICC/IF
-
Reactivity :
Human
-
Formulation:
Supplied in PBS (pH 7.4), containing 50% glycerol, 0.05% BSA, and 0.05% Proclin300.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
Phospho-VAV1 (Tyr174) Antibody (YA10030) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to Phospho-VAV1 (Tyr174).
-
Host Rabbit
-
Clonality Monoclonal,Recombinant
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 98 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 98 kDa
Synthetic Phospho-peptide corresponding to residues surrounding Y174 of human VAV1.
Endogenous
affinity purified.
Non-conjugated
Phosphorylated
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4), containing 50% glycerol, 0.05% BSA, and 0.05% Proclin300.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
VAV1 couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation
-
Expression
Tissue_Specificity: Widely expressed in hematopoietic cells but not in other cell types. -
Isoforms & Post-Translational Modification
Phospho-VAV1 has 2 isoforms, P15498-1: amino acid length is 845, molecular weight is 98314 Da (predicted); P15498-2: amino acid length is 813, molecular weight is 94493 Da (predicted).Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS) (By similarity). Phosphorylated by FYN
-
Subunit
Interacts with SHB.
-
SwissProt ID
-
Synonyms
VAV, VAV1, Proto-oncogene vav
Documentation
Powered by Bioz
