2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. PLTP Antibody (YA2754)

PLTP Antibody (YA2754) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PLTP.

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20 μL Obtener un presupuesto 4 - 5 Weeks 3 - 4 Weeks 5 - 6 Weeks 4 - 5 weeks
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100 μL Obtener un presupuesto 4 - 5 Weeks 3 - 4 Weeks 5 - 6 Weeks 4 - 5 weeks
250 μL   Obtener un presupuesto  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Descripciòn

Descripciòn

PLTP Antibody (YA2754) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PLTP.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Peso molecular
Predicted band size: 55 kDa;
Observed band size: 80 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Rat
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human PLTP aa250-270.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Pureza Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Background
Function：Mediates the transfer of phospholipids and free cholesterol from triglyceride-rich lipoproteins (low density lipoproteins or LDL and very low density lipoproteins or VLDL) into high-density lipoproteins (HDL) as well as the exchange of phospholipids between triglyceride-rich lipoproteins themselves (PubMed:11013307, PubMed:19321130, PubMed:21515415, PubMed:29883800, PubMed:7654777, PubMed:9132017). Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylinositol, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine (PubMed:9132017). Plays an important role in HDL remodeling which involves modulating the size and composition of HDL (PubMed:29883800). Also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion (PubMed:21736953). Two distinct forms of PLTP exist in plasma: an active form that can transfer phosphatidylcholine from phospholipid vesicles to HDL, and an inactive form that lacks this capability (PubMed:11013307)
Subcellular Localization：Secreted; Nucleus
Expression：
Tissue_specificity:Widely expressed. Highest level of expression in the ovary, thymus and placenta, with moderate levels found in the pancreas, small intestine, testis, lung and prostrate. Low level expression in the kidney, liver and spleen, with very low levels found in the heart, colon, skeletal muscle, leukocytes and brain. Expressed in the cortical neurons
Isoforms & Post-Translational Modification：P55058 has 4 isomers: P55058-1: 54739 Da (predicted); P55058-2: 49272 Da (predicted); P55058-3: 44135 Da (predicted); P55058-4: 44847 Da (predicted).
Glycosylation is necessary for secretion and its phospholipid transfer activity
Database

Entrez Gene: 5360 Human ;

SwissProt: P55058 Human ;

OMIM: 172425 Human

Research Field

Cardiovascular
Synonyms
BPIFE; HDLCQ9; OD107; Pltp
Documentación
User Guide for Antibodies (1077 KB)

PLTP Antibody (YA2754) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
PLTP Antibody (YA2754)
Cat. No.:
HY-P83009
Cantidad:
MCE Japan Authorized Agent:

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