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PSMD2 (Proteasome 26S S2) Antibody (YA7816)(PBS only)

(Synonyms: P97; RPN1; S2; TRAP2)

PSMD2 (Proteasome 26S S2) Antibody (YA7816) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PSMD2 (Proteasome 26S S2).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P, ICC/IF

  • Reactivity :

    Human, Dog, Rat, Monkey, Mouse

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PSMD2 (Proteasome 26S S2) Antibody (YA7816)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:150-500 1:100-250

Product Details

Description

PSMD2 (Proteasome 26S S2) Antibody (YA7816) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PSMD2 (Proteasome 26S S2).

  • Host Mouse
  • Species Reactivity
    Human, Dog, Rat, Monkey, Mouse
  • Calculated Molecular Weight Predicted band size: 100 kDa
Immunogen

Full length human recombinant protein of human PSMD2 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PSMD2 component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair|Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1

  • Expression


    Tissue_Specificity: Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta

  • Isoforms & Post-Translational Modification

    Q13200 has three isomers: Q13200-1: 100200 Da (predicted); Q13200-2: 82193 Da (predicted); Q13200-3: 85606 Da (predicted).

  • Subunit

    Component of the 19S proteasome regulatory particle complex

  • SwissProt ID

    Q13200

  • Synonyms

    P97; RPN1; S2; TRAP2

PSMD2 (Proteasome 26S S2) Antibody (YA7816)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • PSMD2 (Proteasome 26S S2) Antibody (YA7816)(PBS only) Product Image
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  • PSMD2 (Proteasome 26S S2) Antibody (YA7816)(PBS only) Product Image