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RAB37 Antibody (YA8307)(PBS only)

(Synonyms: FLJ30284; FLJ32507)

RAB37 Antibody (YA8307) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RAB37.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P, ICC/IF

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • RAB37 Antibody (YA8307)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:150-500 1:100-250

Product Details

Description

RAB37 Antibody (YA8307) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RAB37.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 24 kDa
Immunogen

Full length human recombinant protein of human RAB37 prduced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RAB37 is a The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Acts as an organizer for autophagosome biogenesis in a GTP-dependent manner. Involved in retinal homeostasis by autophagy regulation[1].

  • Subcellular Localization

    Cytoplasmic vesicle,Cell projection, cilium

  • Isoforms & Post-Translational Modification

    Q96AX2 has four isomers: Q96AX2-1: 24815 Da (predicted); Q96AX2-2: 24169 Da (predicted); Q96AX2-3: 25663 Da (predicted); Q96AX2-4: 20894 Da (predicted).

  • Subunit

    Interacts with RIMS1 (By similarity)

  • SwissProt ID

    Q96AX2

  • Synonyms

    FLJ30284; FLJ32507

RAB37 Antibody (YA8307)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • RAB37 Antibody (YA8307)(PBS only) Product Image