RHOJ Antibody (YA8314)
(Synonyms: ARHJ; RASL7B; TC10B; TCL)RHOJ Antibody (YA8314) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RHOJ.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
RHOJ Antibody (YA8314) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RHOJ.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 23.6 kDa
Full length human recombinant protein of human RHOJ produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RHOJ is a Plasma membrane-associated small GTPase specifically involved in angiogenesis. Required for endothelial cell migration during vascular development via its interaction with GLUL. Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration[1][2][3].
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Subcellular Localization
Cell membrane
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Expression
Tissue_Specificity: Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver
Induction: Expression is regulated by the transcription factor ERG -
Isoforms & Post-Translational Modification
Q9H4E5 has two isomers: Q9H4E5-1: 23821 Da (predicted); Q9H4E5-2: 21255 Da (predicted).
Palmitoylated; regulates localization to the plasma membrane and may be mediated by GLUL -
Subunit
Interacts with the CRIB domains of proteins such as Pak1 and Was/Wasp (By similarity)
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SwissProt ID
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Synonyms
ARHJ; RASL7B; TC10B; TCL
Documentation
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